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  • Title: T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals.
    Author: Iwai LK, Yoshida M, Sadahiro A, da Silva WR, Marin ML, Goldberg AC, Juliano MA, Juliano L, Shikanai-Yasuda MA, Kalil J, Cunha-Neto E, Travassos LR.
    Journal: Clin Vaccine Immunol; 2007 Apr; 14(4):474-6. PubMed ID: 17329443.
    Abstract:
    Vaccines with synthetic peptides induce the immune response to epitopes that bind to several HLA alleles. By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM.
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