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  • Title: Intracerebral, aortic, and umbilical artery flow velocity waveforms in the late-first-trimester fetus.
    Author: Wladimiroff JW, Huisman TW, Stewart PA.
    Journal: Am J Obstet Gynecol; 1992 Jan; 166(1 Pt 1):46-9. PubMed ID: 1733217.
    Abstract:
    OBJECTIVES: Our objectives were to determine the success rate in obtaining flow velocity waveforms in the first-trimester fetal circulation and to establish possible preferential flow to the fetal cerebrum at this early stage of gestation. STUDY DESIGN: Flow velocity waveform recordings were made in the umbilical artery, fetal descending aorta, and fetal intracerebral arteries in 30 normal pregnancies between 11 and 13 weeks of gestation. RESULTS: Technically acceptable waveforms were obtained from the descending aorta in 15 fetuses, from the intracerebral circulation in 17 fetuses, and from the umbilical artery in all 30 fetuses. Absent end-diastolic velocities in the descending aorta and umbilical artery were associated with forward flow throughout the cardia cycle in intracerebral arteries. CONCLUSION: A relatively low cerebral vascular resistance in the late-first-trimester normal fetus is suggested.
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