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  • Title: Kaposi's sarcoma in Nigeria.
    Author: Onunu AN, Okoduwa C, Eze EU, Adeyekun AA, Kubeyinje EP, Schwartz RA.
    Journal: Int J Dermatol; 2007 Mar; 46(3):264-7. PubMed ID: 17343581.
    Abstract:
    BACKGROUND: The prevalence of Kaposi's sarcoma (KS) in parts of Africa has been on the increase as a result of the human immunodeficiency virus (HIV) infection pandemic. However, there is a paucity of information for Nigeria. OBJECTIVE: To describe the clinical and epidemiological characteristics of cutaneous KS in patients with HIV-infection in Benin City, Nigeria. METHODS: All patients presenting to the dermatology and infectious diseases clinics of the University of Benin Teaching Hospital, or admitted to its medical wards, within the period July 2000-June 2005 were examined retrospectively in a chart review for KS. Diagnosis of HIV was based upon ELISA testing. The CD4(+) cell counts were performed using the Dyna Bead method and KS was diagnosed histologically. RESULTS: In our survey, 31 patients, representing 0.84% of all new HIV patients seen during the study period, had cutaneous KS. There were 19 males and 12 females, giving a male to female ratio of 1.6 : 1. The mean age was 36.3 +/- 9 years; mean CD4(+) count was 127 +/- 14 cells/dl. The lower limbs (74.2%), trunk (48.4%) and the face (22.6%) were the most frequent sites affected. The lesions were solitary in three patients (9.7%) and multiple in 28 patients (90.3%). CONCLUSION: The prevalence of HIV-related KS is increasing in Nigeria. There is an increase in the number of women being diagnosed with this form of KS, probably owing to more females having HIV disease.
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