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  • Title: Borreliacidal OspC antibody response of canines with Lyme disease differs significantly from that of humans with Lyme disease.
    Author: Lovrich SD, La Fleur RL, Jobe DA, Johnson JC, Asp KE, Schell RF, Callister SM.
    Journal: Clin Vaccine Immunol; 2007 May; 14(5):635-7. PubMed ID: 17344346.
    Abstract:
    Humans reliably produce high concentrations of borreliacidal OspC antibodies specific for the seven C-terminal amino acids shortly after infection with Borrelia burgdorferi. We show that dogs also produce OspC borreliacidal antibodies but that their frequencies, intensities, and antigenicities differ significantly. The findings therefore confirm a major difference between the borreliacidal antibody responses of humans and canines with Lyme disease.
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