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  • Title: [Clinical variability and characteristics of attention deficit hyperactivity disorder in girls].
    Author: Valdizán JR, Mercado E, Mercado-Undanivia A.
    Journal: Rev Neurol; 2007 Mar 02; 44 Suppl 2():S27-30. PubMed ID: 17347940.
    Abstract:
    INTRODUCTION: Attention deficit hyperactivity disorder (ADHD) is a neurobiological condition essentially characterised by inattention, hyperactivity and impulsiveness, and has a prevalence of around 5%. Because it is a biological disorder, both boys and girls with ADHD display these same symptoms, but more boys are diagnosed with ADHD (in a ratio of 3 to 1). AIM: To examine the differences between the two sexes, their prevalence and possible female subtypes in ADHD. PATIENTS AND METHODS: We conducted a retrospective study of 172 patients of both sexes who were attended as hospital neuropaediatric outpatients in the year 2004 according to Diagnostic and statistical manual of mental disorders (DSM-IV-TR) criteria. Their ages ranged between 4 and 14 years and they were divided into three groups: under 6, between 6 and 10, and from 11 to 14 years old. The girls were subdivided into four subtypes, in order of greater to lesser prevalence: shy, hypersociable, hyperactive and changeable. RESULTS: Both sexes showed the same response to methylphenidate. Only the group of boys presented other comorbidities such as negativism and conduct disorders; approximately 25% of them required treatment with atypical neuroleptic drugs. CONCLUSIONS: a) Girls have certain specific clinical manifestations within the three common symptoms; b) methylphenidate is equally effective in both sexes; c) only boys display other disorders such as negativism and conduct disorders; and d) the brains of males and females are quite similar, but symptoms are expressed differently depending on environments and levels.
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