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  • Title: A case of xanthomatosis and hyperlipoproteinemia type V propably induced by overdosage of insulin.
    Author: Vermeer BJ, Poland MK.
    Journal: Dermatologica; 1975; 151(1):43-50. PubMed ID: 173587.
    Abstract:
    A woman, aged 46 years, with a hyperlipoproteinemia phenotype V, an unusual type of xanthomatosis, as well as lipemia retinalis, diabetes mellitus, and nephropathia, is discussed. The withdrawal of 64 IU insulin and the institution of a hypocaloric diabetes diet resulted in the disappearance of the skin lesions and a regression of the eye lesion. During this treatment the total lipid-level became almost normal (6,965 mg% before treatment and 947 mg% after 10 weeks). The chylomicrons disappeared but the VLDL content remained relatively and absolutely elevated, as in type IV hyperlipoproteinemia.
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