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  • Title: Event-related potentials to visual, auditory, and bimodal (combined auditory-visual) stimuli.
    Author: Isoğlu-Alkaç U, Kedzior K, Keskindemirci G, Ermutlu N, Karamursel S.
    Journal: Int J Neurosci; 2007 Feb; 117(2):259-73. PubMed ID: 17365112.
    Abstract:
    The purpose of this study was to investigate the response properties of event related potentials to unimodal and bimodal stimulations. The amplitudes of N1 and P2 were larger during bimodal evoked potentials (BEPs) than auditory evoked potentials (AEPs) in the anterior sites and the amplitudes of P1 were larger during BEPs than VEPs especially at the parieto-occipital locations. Responses to bimodal stimulation had longer latencies than responses to unimodal stimulation. The N1 and P2 components were larger in amplitude and longer in latency during the bimodal paradigm and predominantly occurred at the anterior sites. Therefore, the current bimodal paradigm can be used to investigate the involvement and location of specific neural generators that contribute to higher processing of sensory information. Moreover, this paradigm may be a useful tool to investigate the level of sensory dysfunctions in clinical samples.
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