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  • Title: Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma.
    Author: Rajkumar SV, Lacy MQ, Kyle RA.
    Journal: Blood Rev; 2007 Sep; 21(5):255-65. PubMed ID: 17367905.
    Abstract:
    Monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) are asymptomatic disorders characterized by monoclonal plasma cell proliferation in the bone marrow in the absence of end-organ damage. Updated diagnostic criteria for these disorders, risk-stratification models to determine prognosis, and the current management of these two entities are discussed in this review.
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