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  • Title: [Two cases of Pseudomonas aeruginosa neonatal meningitis treated by ciprofloxacine].
    Author: Tanase-Derkaoui D, le Huidoux P, Farnoux C, El-Moussawi F, Mariani-Kurkdjian P, Bingen E, Baud O, Aujard Y.
    Journal: Arch Pediatr; 2006 Oct; 13 Suppl 1():S17-21. PubMed ID: 17370392.
    Abstract:
    Two cases of Pseudomonas aeruginosa neonatal meningitis are reported. Case 1 occurred on day 6 of life, at home, in a full term newborn. Favourable outcome was obtained with a treatment associating ceftazidime, 21 days, gentamicin, 10 days and ciprofloxacin, 10 days. Case no 2 was a nosocomial meningitis in a 32 weeks and 4 days gestational age premature newborn. Despite in vitro effective antibiotherapy with ceftazidime, netilmicine and ciprofloxacine, six cerebral abscesses were observed during the second week of treatment. Ceftazidime was stopped after 6 weeks and ciprofloxacine prolonged until neuroradiological cure of cerebral lesions at one year of age. Normal outcome was observed at 3 and 4 and half year of age. Therapeutic indications and clinical tolerance of ciprofloxacine in neonatal meningitis are discussed.
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