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  • Title: Use of neostigmine to relieve a suspected colonic pseudoobstruction in pregnancy.
    Author: Rausch ME, Troiano NH, Rosen T.
    Journal: J Perinatol; 2007 Apr; 27(4):244-6. PubMed ID: 17377607.
    Abstract:
    Neostigmine is a treatment option for colonic pseudoobstruction. However, experience in using neostigmine for this indication in pregnant women is limited. We present a case of a woman with an estimated fetal gestational age of 34 weeks presented with what was believed to be a pseudoobstruction and when conservative management failed, neostigmine was administered with no adverse side effects. Ultimately, the patient was found to have a mechanical obstruction and we discuss the challenges in making this diagnosis in pregnancy. Neostigmine may be a viable alternative to colonoscopy in pregnant women for whom mechanical obstruction is properly excluded.
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