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Title: Scutiaquinones A and B, perylenequinones from the roots of Scutia myrtina with anthelmintic activity. Author: Ayers S, Zink DL, Mohn K, Powell JS, Brown CM, Murphy T, Brand R, Pretorius S, Stevenson D, Thompson D, Singh SB. Journal: J Nat Prod; 2007 Mar; 70(3):425-7. PubMed ID: 17378532. Abstract: Haemonchus contortus is a worm that causes serious infections in livestock. Two new perylenequinones, scutiaquinone A (1) and scutiaquinone B (2), have been isolated from a methanol extract of the roots of Scutia myrtina by bioassay-guided fractionation, using an assay that kills this parasite in vitro. The structures of compounds 1 and 2 were elucidated by analysis of their 1D- and 2D-NMR and MS spectra. The isolation, structure, and anthelmintic activities of compounds 1 and 2 are reported.[Abstract] [Full Text] [Related] [New Search]