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  • Title: Neutrophilic dermatosis resembling pyoderma gangrenosum in a dog with polyarthritis.
    Author: Bardagí M, Lloret A, Fondati A, Ferrer L.
    Journal: J Small Anim Pract; 2007 Apr; 48(4):229-32. PubMed ID: 17381769.
    Abstract:
    This report describes a case of neutrophilic dermatosis in a dog, with a number of clinical and pathological similarities to human pyoderma gangrenosum. A seven-year-old, female German shepherd dog with a history of non-erosive idiopathic polyarthritis was presented with severe facial swelling, bilateral erosivoulcerative lesions on the muzzle and multiple, eroded, dermal-subcutaneous nodules on the cranial trunk. Histopathological examination of skin biopsies revealed a necrotising neutrophilic dermatitis. No infectious agents could be detected using specific stains, immunohistochemistry, serology and bacterial aerobic, anaerobic or fungal cultures. A sterile neutrophilic dermatosis resembling human pyoderma gangrenosum was presumptively diagnosed, and the patient showed an excellent response to treatment with prednisone and ciclosporin.
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