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  • Title: Fisher/Gullain-Barré overlap syndrome in advanced AIDS.
    Author: Hiraga A, Kuwabara S, Nakamura A, Yuki N, Hattori T, Matsunaga T.
    Journal: J Neurol Sci; 2007 Jul 15; 258(1-2):148-50. PubMed ID: 17391707.
    Abstract:
    Human immunodeficiency virus-associated Guillain-Barré syndrome typically occurs early in HIV infection before AIDS develops. We report a 56-year-old male AIDS patient, who developed overlapping Fisher/Guillain-Barré syndrome despite markedly decreased CD4 cell counts. Serum anti-GQ1b IgG antibody was positive. His condition improved rapidly after immunoglobulin treatment. This indicates that Fisher/Guillain-Barré syndrome may occur even in severely immunosuppressed patients and that anti-ganglioside antibody production is possibly mediated by a T cell-independent process.
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