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  • Title: Laparoscopic splenectomy in a pregnant patient with immune thrombocytopenic purpura.
    Author: Felbinger TW, Posner M, Eltzschig HK, Kodali BS.
    Journal: Int J Obstet Anesth; 2007 Jul; 16(3):281-3. PubMed ID: 17399979.
    Abstract:
    We describe the perioperative management of a pregnant woman at 19 weeks' gestation with idiopathic thrombocytopenic purpura requiring laparoscopic splenectomy. The preoperative platelet count ranged between 1 and 5 x 10(9)/L and did not respond to conventional medical therapy. To reduce the risk of intracerebral hemorrhage, platelets were transfused before induction of anesthesia to maintain platelet count closer to 20 x 10(9)/L. The blood pressure was monitored continuously via an arterial line and remifentanil was infused to prevent a hypertensive response to induction/intubation, carbon dioxide insufflation, and surgery. After the splenic artery was clamped, additional platelet units were transfused to assure surgical hemostasis.
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