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  • Title: Lysostaphin in treatment of neonatal Staphylococcus aureus infection.
    Author: Oluola O, Kong L, Fein M, Weisman LE.
    Journal: Antimicrob Agents Chemother; 2007 Jun; 51(6):2198-200. PubMed ID: 17420212.
    Abstract:
    This study describes lysostaphin's effect against methicillin-sensitive Staphylococcus aureus in suckling rats. Standard techniques determined minimal inhibitory and bactericidal concentrations, pharmacokinetics, and efficacy. The numbers of surviving rats after vancomycin, oxacillin, and lysostaphin treatment were comparable and were different from that of controls (P < 0.00001). Lysostaphin appears effective in the treatment of neonatal S. aureus infection.
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