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  • Title: [Clinical features of thyrotoxic heart disease: analysis of 75 cases].
    Author: Wu HH, Guo XH, Gao YM.
    Journal: Zhonghua Yi Xue Za Zhi; 2007 Jan 23; 87(4):262-4. PubMed ID: 17425873.
    Abstract:
    OBJECTIVE: To investigate the clinical features of thyrotoxic heart disease. METHODS: The clinical data of 75 patients with thyrotoxic heart disease, 30 males and 45 females, aged 54.3 +/- 14.4 (17 approximately 84, with the course from 1 month to 30 years, were analyzed retrospectively. RESULTS: Forty-seven of the 75 patients (63%)presented heart failure, 47 patients (63%) showed atrial fibrillation, 2 patients (3%) showed sick sinus syndrome; 48 patients (66%) showed left atrial enlargement, 31 (43%) showed left ventricular enlargement, 30 (41%) showed right atrial enlargement, 35 (47%) showed right ventricular enlargement, and 18 (25%) showed entire heart enlargement. Mitral valve regurgitation occurred in 45 patients, tricuspid regurgitation in 45, aortic valve regurgitation in 34, and pulmonary artery hypertension (with the pulmonary blood pressure of 44 +/- 7 mm Hg and LVEF of 60% +/- 19%) in 33 patients. CONCLUSION: The clinical manifestations of thyrotoxic heart disease are various Thyroid function should be investigated to exclude thyrotoxic heart disease when routine treatment is ineffective in heart disease. The key point of treatment is hyperthyroidism.
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