These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The quantitative immunoturbidimetric D-dimer method to rule out venous thromboembolism (VTE).
    Author: Elhabyan A, Broce M, Rosencrance JG, Lucas BD, Nakker S, Reyes BJ.
    Journal: W V Med J; 2007; 103(1):22-5. PubMed ID: 17432312.
    Abstract:
    D-dimer measurement is a technique that may improve the diagnostic strategy for venous thrombo-embolism (VTE). To evaluate D-dimer accuracy in the diagnosis of VTE, we identified 116 patients at Charleston Area Medical Center in Charleston, W.Va., for whom D-dimer assay had been performed to screen for VTE. Forty-one had VTE diagnosis confirmed (VTE-Positive); and 75 were ruled out (VTE-Negative); all by radiologic studies. D-dimer values for 41 healthy individuals were also prospectively collected. D-dimer value ranges of VTE-Positive, VTE-Negative and Healthy Sample groups were 0.5-55, 0.5-15.9, and 0.4-3.24 mg/L. Cutoff values of 2.5, 2.1, 1.6, and 1 mg/L had sensitivities of 74%, 81%, 86% and 95%, with specificities of 60%, 48%, 32% and 12%, respectively. Negative predictive values were 80%, 81%, 79% and 82%, while positive predictive values were 52%, 48%, 43% and 39%, respectively. Our results show that quantitative D-dimer assays lack the accuracy to serve as a method for ruling out VTE.
    [Abstract] [Full Text] [Related] [New Search]