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  • Title: Ectopic pregnancy rates with frozen compared with fresh blastocyst transfer.
    Author: Jun SH, Milki AA.
    Journal: Fertil Steril; 2007 Sep; 88(3):629-31. PubMed ID: 17434510.
    Abstract:
    OBJECTIVE: To compare the rate of ectopic pregnancy (EP) with fresh versus frozen blastocyst transfer in our program during the same time period. DESIGN: Retrospective analysis. SETTING: University IVF program. PATIENT(S): Women who achieved a clinical pregnancy after IVF between 1998 and 2005. INTERVENTION(S): In our program, cryopreservation is performed at the blastocyst stage. Embryo transfer was performed 1 to 1.5 cm short of the fundus by abdominal ultrasound guidance. MAIN OUTCOME MEASURE(S): The incidence of EP was examined in relation to fresh versus frozen blastocyst transfer. RESULT(S): In the frozen blastocyst group, there were 5 EPs out of 180 clinical pregnancies (2.8%), and there were 10 EPs out of 564 clinical pregnancies (1.8%) in the fresh blastocyst group. CONCLUSION(S): The rate of EP is not significantly increased after the transfer of frozen thawed blastocysts compared with fresh blastocyst transfer.
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