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  • Title: A case of relapsing polychondritis with bilateral sensorineural hearing loss and perforation of the nasal septum at the onset.
    Author: Tsuda T, Nakajima A, Baba S, Tanohara K, Masuda I, Yamada T, Takagi K, Yamakawa T, Kamatani N, Hara M.
    Journal: Mod Rheumatol; 2007; 17(2):148-52. PubMed ID: 17437171.
    Abstract:
    A 33-year-old woman suffered from epistaxis and perforation of the nasal septum. Based on a biopsy of nasal mucosa, Wegener's granulomatosis was suspected initially. Her nasal symptoms improved spontaneously, but tinnitus, hearing loss, and dizziness appeared within 3 months. Laboratory analyses revealed no inflammation, and antineutrophil cytoplasmic antibodies were negative. Audiometry revealed bilateral sensorineural hearing loss. A second biopsy of the nasal septum showed an inflammatory change in the cartilage. Thus we diagnosed early-stage relapsing polychondritis.
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