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  • Title: The use of unsymmetrical indirect covariance NMR methods to obtain the equivalent of HSQC-NOESY data.
    Author: Blinov KA, Williams AJ, Hilton BD, Irish PA, Martin GE.
    Journal: Magn Reson Chem; 2007 Jul; 45(7):544-6. PubMed ID: 17437315.
    Abstract:
    We have recently demonstrated that unsymmetrical indirect covariance NMR methods can be used to mathematically calculate the equivalent of low sensitivity, hyphenated NMR experiments by combining data from a pair of higher sensitivity experiments. The present report demonstrates the application of this method to the combination of HSQC and NOESY spectra to provide results comparable to HSQC-NOESY data, albeit with greater sensitivity and with considerably less spectrometer time.
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