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  • Title: Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis.
    Author: Shen X, Shen GM, Wu J, Gui XH, Li X, Mei J, DeRiemer K, Gao Q.
    Journal: Antimicrob Agents Chemother; 2007 Jul; 51(7):2618-20. PubMed ID: 17438044.
    Abstract:
    embB306 mutants were detected in both ethambutol (EMB)-resistant and EMB-susceptible strains of Mycobacterium tuberculosis. Multidrug-resistant (MDR) strains had a higher proportion of embB306 mutants than non-MDR strains (odds ratio, 6.78; P < 0.001). The embB306 locus is a candidate marker for rapid detection of MDR and extremely drug resistant tuberculosis.
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