These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Microwave-assisted heterogeneous cross-coupling reactions catalyzed by nickel-in-charcoal (Ni/C).
    Author: Lipshutz BH, Frieman BA, Lee CT, Lower A, Nihan DM, Taft BR.
    Journal: Chem Asian J; 2006 Sep 18; 1(3):417-29. PubMed ID: 17441078.
    Abstract:
    A study involving the relatively rare combination of heterogeneous catalysis conducted under microwave conditions is presented. Carbon-carbon bond formation, including Negishi and Suzuki couplings, can be quickly effected with aryl chloride partners by using a base metal (nickel) adsorbed in the pores of activated charcoal. Aminations were also studied, along with cross-couplings of vinyl alanes with benzylic chlorides as a means to stereodefined allylated aromatics. Reaction times for all these processes are typically reduced from several hours to minutes in a microwave reactor.
    [Abstract] [Full Text] [Related] [New Search]