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  • Title: [Perioperative treatment of a patient with ectopic ACTH-producing pheochromocytoma].
    Author: Shigekawa T, Sato T, Mizobuchi S, Nakatsuka H, Yokoyama M, Morita K.
    Journal: Masui; 2007 Apr; 56(4):442-5. PubMed ID: 17441456.
    Abstract:
    This report deals with perioperative treatment for a very rare disease called ectopic ACTH-producing pheochromocytoma in a 55-year-old woman. She showed high norepinephrine, cortisol, and ACTH levels, and diagnosed as ectopic ACTH-producing pheochromocytoma, by MIBG scintigraphy. An alpha-blocker and fluid loading for pheochromocytoma, and an adrenal cortex hormone synthesis inhibitor for Cushing's syndrome, were given simultaneously as a preoperative treatment. Propofol with nitrous oxide-oxygen-sevoflurane and epidural anesthesia were used for excision of the tumor, and the procedure was performed without any marked changes in hemodynamics. Although ectopic ACTH-producing pheochromocytoma is a very rare disease, it can be managed safely by appropriate preoperative treatment for pheochromocytoma and Cushing's syndrome.
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