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  • Title: MR findings of intrathecal chemotherapy-related myelopathy in two cases: mimicker of subacute combined degeneration.
    Author: Lu CH, Yao M, Liu HM, Chen YF.
    Journal: J Neuroimaging; 2007 Apr; 17(2):184-7. PubMed ID: 17441843.
    Abstract:
    We report the findings of spinal magnetic resonance imaging (MRI) in 2 patients who had undergone intrathecal chemotherapy and presented with the subacute onset of ascending numbness and weakness. MRI revealed a symmetric hyperintensity at the posterior columns of the spinal cord from the lower cervical region down to the conus medullaris level on T2-weighted images, and no abnormal enhancement. The imaging findings are similar to those seen in subacute combined degeneration (SCD), but the serum vitamin B(12) levels were normal in these 2 cases.
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