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  • Title: A case of hypertrophic pachymeningitis with prolonged headache, attributable to Epstein-Barr virus.
    Author: Okuma H, Kobori S, Shinohara Y, Takagi S.
    Journal: Headache; 2007 Apr; 47(4):620-2. PubMed ID: 17445115.
    Abstract:
    Hypertrophic pachymeningitis is a condition characterized by significant chronic inflammatory thickening of the cranial dura mater, frequently presenting with symptoms such as headache and cranial neuropathy. In this report, we describe a very rare case of hypertrophic pachymeningitis, considered to be attributable to Epstein-Barr virus (EBV), which was diagnosed in a patient who visited our hospital with a complaint of ongoing severe headaches. The diagnosis was based on positive specific serum EBV antibody titers, with VCA-IgM levels of less than 1:10, VCA-IgG levels of 1:160, and EBNA levels of 1:40, as well as on the results of magnetic resonance imaging of the head with contrast media.
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