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Title: Oral and maxillofacial manifestations of Gardner's syndrome associated with growth hormone deficiency: case report and literature review. Author: Ramaglia L, Morgese F, Filippella M, Colao A. Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2007 Jun; 103(6):e30-4. PubMed ID: 17449294. Abstract: Gardner's syndrome (GS) is a hereditary disorder inherited as autosomal dominant with complete penetrance and variable expression. GS is a variant of familial adenomatous polyposis characterized by extracolonic manifestations including osteomas, dental anomalies, and epidermoid cysts. The association between GS and endocrine abnormalities has been well documented but a direct pituitary involvement has never been reported. We present a case of oral and maxillofacial manifestations in an adult patient affected by GS associated with growth hormone deficiency, a hitherto unreported association. The possible pathogenic mechanisms are discussed.[Abstract] [Full Text] [Related] [New Search]