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Title: In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents. Author: Almyroudis NG, Sutton DA, Fothergill AW, Rinaldi MG, Kusne S. Journal: Antimicrob Agents Chemother; 2007 Jul; 51(7):2587-90. PubMed ID: 17452481. Abstract: We evaluated the in vitro susceptibilities of 217 zygomycetes to amphotericin B, ketoconazole, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and flucytosine. The significant in vitro activity of posaconazole against several species appears to support its reported clinical efficacy. Decreased susceptibility to amphotericin B was noted with Cunninghamella bertholletiae.[Abstract] [Full Text] [Related] [New Search]