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Title: Effects of selective cochlear toxicity and vestibular deafferentation on vestibular evoked myogenic potentials in guinea pigs. Author: Shojaku H, Zang RL, Tsubota M, Fujisaka M, Hori E, Nishijo H, Watanabe Y. Journal: Acta Otolaryngol; 2007 Apr; 127(4):430-5. PubMed ID: 17453466. Abstract: CONCLUSION: The findings suggest that sound-evoked myogenic potentials on the guinea pig sternocleidomastoid muscle (SM) originate from the vestibular end organ and not from the cochlea of the inner ear. OBJECTIVE: Studies in animals of the sound evoked vestibular myogenic potentials on the SM should aid in elucidating the pathway of the vestibular-evoked myogenic potential (VEMP). However, details of the pathway of the VEMP remain to be elucidated. This study aimed to clarify aspects of this pathway. MATERIALS AND METHODS: In the present study, short latency biphasic myogenic potentials on the SM in guinea pigs were induced by an intense brief sound. RESULTS: The thresholds of the potentials were 67 dB SPL above those of the auditory brainstem response (ABR). The potentials were eliminated by a vestibular deafferentation, but were observed after selective cochlea toxicity using an amikacin injection.[Abstract] [Full Text] [Related] [New Search]