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  • Title: Influence of dietary fatty acids on phospholipid composition and prostaglandin E synthesis in rat kidneys.
    Author: Maranesi M, Barzanti V, Cocchi M, Biagi G, Coccheri S, Turchetto E.
    Journal: Prostaglandins Leukot Essent Fatty Acids; 1991 Oct; 44(2):93-6. PubMed ID: 1745657.
    Abstract:
    The effects of oils with different amounts of n6 and n3 fatty acid precursors and derivatives were evaluated on phospholipid composition and PGE2 synthesis of rat kidneys. Dietary lipids were: olive oil, an olive-blackcurrant-fish oil mixture and a blackcurrant-fish oil mixture. We observed in the kidneys of rats fed the blackcurrant-fish oil mixture a significant decrease in PGE2 synthesis, while arachidonate values did not show significant variations. A decrease of PGE2 synthesis could be due to competitive and inhibitory effects of fatty acids other than arachidonate, observed in the kidney phospholipid composition in our dietary conditions.
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