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  • Title: Controversy and conflict in the treatment of acute decompensated heart failure: nesiritide as evidence-based treatment.
    Author: Munger MA, Ng TM, Van Tassell BW.
    Journal: Pharmacotherapy; 2007 May; 27(5):619-25. PubMed ID: 17461695.
    Abstract:
    Acute decompensated heart failure poses a complex clinical challenge for the health care community. Evolving concepts of the pathophysiology and lack of consensus on appropriate outcome measures for drug approval underlie some of the current controversies about nesiritide. We outline the major controversies from the viewpoint that nesiritide should continue to be used judiciously by following its package insert recommendations and the Heart Failure Society of America's 2006 Comprehensive Heart Failure Practice Guidelines.
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