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  • Title: Serum antibodies to the pneumococcal surface proteins PhtB and PhtE in Finnish infants and adults.
    Author: Holmlund E, Simell B, Jaakkola T, Lahdenkari M, Hamel J, Brodeur B, Kilpi T, Käyhty H.
    Journal: Pediatr Infect Dis J; 2007 May; 26(5):447-9. PubMed ID: 17468659.
    Abstract:
    We examined naturally acquired antibodies to pneumococcal vaccine candidate proteins PhtB and PhtE in children during their first 2 years of life. Prior culture-confirmed pneumococcal exposure was shown to induce the development of anti-PhtB and -PhtE antibodies. The anti-PhtB or -PhtE antibody concentrations were not significantly associated with a decreased risk of subsequent pneumococcal acute otitis media.
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