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  • Title: Treatment of feline hypertension with transdermal amlodipine: a pilot study.
    Author: Helms SR.
    Journal: J Am Anim Hosp Assoc; 2007; 43(3):149-56. PubMed ID: 17473021.
    Abstract:
    This prospective study evaluated transdermal amlodipine for the control of hypertension in six cats. Cats were treated with oral amlodipine until blood pressures decreased to <180 mm Hg. They were maintained on this dose for 7 days and then administered identical doses of transdermal amlodipine for 7 days. Oral amlodipine decreased pressure by a median of 73 mm Hg, which subsequently increased by 20 mm Hg after 7 days of transdermal amlodipine. Plasma concentrations of amlodipine were measured after oral and transdermal dosing. Additional studies are needed to determine dosing, pharmacokinetics, and efficacy.
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