These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Role of abdominal muscles activity on duration and severity of hypoxemia episodes in mechanically ventilated preterm infants.
    Author: Esquer C, Claure N, D'Ugard C, Wada Y, Bancalari E.
    Journal: Neonatology; 2007; 92(3):182-6. PubMed ID: 17476118.
    Abstract:
    BACKGROUND: Episodes of hypoxemia are often observed in ventilated preterm infants. The factors that determine their duration, severity and the failure of the mechanical breaths to maintain ventilation have not been fully defined. OBJECTIVE: To determine the relation between activity of the abdominal muscles and the duration and severity of hypoxemia episodes in ventilated preterm infants. METHODS: Clinically stable ventilated preterm infants weighing between 500 and 1,000 g at birth, who presented with frequent episodes of hypoxemia, were studied. Recordings of arterial oxygen saturation (SpO(2)), tidal volume and abdominal surface electromyography were obtained during 4 h to assess the temporal relationship between activation of abdominal musculature with the onset, duration and severity of hypoxemia episodes. RESULTS: In 15 infants, GA (mean +/- SD) 25 +/- 1.5 weeks, BW 697 +/- 141 g, age 37 +/- 14 days, synchronized intermittent mandatory ventilation rate 17 +/- 6 breaths/min, peak inspiratory pressure 18 +/- 1.9 cm H(2)O, positive end-expiratory pressure 4.8 +/- 0.6 cm H(2)O, and fraction of inspired oxygen (FiO(2)) 0.4 +/- 0.1 were studied. These infants presented with 7.2 +/- 4.4 episodes of hypoxemia (SpO(2) <88%) per hour. The number of abdominal muscle contractions per episode correlated with the duration and severity of the episodes of hypoxemia. The episode duration increased by 14 +/- 18 s per abdominal muscle contraction. The lowest SpO(2) reached during an episode of hypoxemia decreased by 1.7 +/- 1.4% for every abdominal muscle contraction. CONCLUSIONS: These data document a relationship between abdominal muscles contraction and the duration and severity of hypoxemia episodes in ventilated preterm infants. These findings can explain the failure of mechanical ventilation to prevent their occurrence or decrease their severity.
    [Abstract] [Full Text] [Related] [New Search]