These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Analysis of the distribution of the nucleotide sequence and electrostatic potential of the Escherichia coli genome].
    Author: Sorokin AA, Osipov AA, Beskaravaĭnyĭ PM, Kamzolova SG.
    Journal: Biofizika; 2007; 52(2):223-7. PubMed ID: 17477048.
    Abstract:
    The oligonucleotide composition of the E. coli genome and its sigma70-specific promoters has been analyzed. The promoter DNA was shown to contain mainly AT-rich hexanucleotides having functionally important physical properties such as the ability to form easily melting sites and induce the bending of the double helix. A comparative analysis of the electrostatic characteristics of hexanucleotides within the whole sequence of the E. coli genome and its promoter regions was made. Hexanucleotides possessing a more electronegative surrounding were found to predominate in the nucleotide sequence of the promoter DNA.
    [Abstract] [Full Text] [Related] [New Search]