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  • Title: Renal tuberculosis in adult polycystic kidney disease: report of 2 cases and review of the literature.
    Author: Simões do Espírito Santo K, Teixeira Vde P, Costa Hde O, Franco M.
    Journal: Int J Surg Pathol; 2007 Apr; 15(2):196-8. PubMed ID: 17478782.
    Abstract:
    Adult polycystic kidney disease (APKD) is a common and potentially fatal disease, leading to end-stage renal failure in 50% of cases. The disease is frequently complicated by arterial hypertension, bacterial pyelonephritis, and hematuria. The association between APKD and tuberculosis has rarely been reported and is related to a more unfavorable course since the infection becomes refractory to specific treatment. The authors report 2 cases of renal tuberculosis diagnosed in the native nephrectomy specimens of 2 patients with APKD after renal transplantation. Tuberculosis, although not common, must be recognized as a potential source of infection of native polycystic kidneys in immunocompromised transplant recipients.
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