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  • Title: Prevalence of glaucoma in patients with obstructive sleep apnoea--a cross-sectional case-series.
    Author: Bendel RE, Kaplan J, Heckman M, Fredrickson PA, Lin SC.
    Journal: Eye (Lond); 2008 Sep; 22(9):1105-9. PubMed ID: 17479120.
    Abstract:
    AIM: To determine the prevalence of glaucoma in patients with obstructive sleep apnoea. DESIGN: Cross-sectional case series. PARTICIPANTS: One hundred patients with moderate to severe obstructive sleep apnoea. TESTING: Within 48 h of the polysomnographic diagnosis of obstructive sleep apnoea, patients underwent the following tests: intraocular pressure, gonioscopy, automated perimetry, stereoscopic biomicroscopy, and fundascopic assessment for the presence of glaucomatous optic nerve changes. MAIN OUTCOME MEASURES: The prevalence of glaucoma in patients with obstructive sleep apnoea and the associations between patient characteristics and both glaucoma and intraocular pressure. RESULTS: Glaucoma was diagnosed in 27 of 100 patients yielding an estimated prevalence of 27% (95% CI 19-37%). The presence of glaucoma did not correlate with sex, body mass index (BMI), or AHI, but did appear to be associated with age (P=0.014). There was no evidence of a relationship between intraocular pressure and either the apnoea plus hypopnoea index or age. CONCLUSION: The prevalence of glaucoma in patients with obstructive sleep apnoea is an estimated 27%. Sex, age, body mass index or apnoea plus hypopnoea index are not factors influencing the presence of glaucoma in this population of patients.
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