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  • Title: Quality control in antimicrobial disk susceptibility testing: a Belgian multicenter study.
    Author: Lauwers S, Philippe J, Van Zeebroeck A, Pierard D, Derde MP, Kaufman L.
    Journal: Eur J Clin Microbiol Infect Dis; 1991 Aug; 10(8):652-6. PubMed ID: 1748119.
    Abstract:
    A Belgian multicenter trial was conducted to evaluate problems encountered with quality control results of antimicrobial disk susceptibility testing and to compare the performance of BBL disks and Rosco tablets. Over a period of four weeks 18 laboratories daily tested three reference strains against eight antibiotics. A standardised method was used by all participants. For all results together 10.4% and 7.3% of the measurements with BBL disks and Rosco tablets, respectively, were outside the recommended range. Major problems were observed for some specific strain-antibiotic combinations. Standard deviations were similar for both systems; their precision was comparable. The results suggest that cooperation between manufacturers and some reference laboratories could be improved in order to establish optimal quality control limits.
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