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  • Title: [Primary liver carcinogenesis induced by the pesticide 2-(4-tert-butylphenoxy0-1-methylethyl 2-chloroethyl sulphite (Aramite)].
    Author: Claude JR, Huyen VN, Warnet JM, Blanc F.
    Journal: C R Acad Hebd Seances Acad Sci D; 1975 Sep 01; 281(9):599-604. PubMed ID: 174832.
    Abstract:
    Wistar rats were fed, during 56 weeks, a diet containing 5 g/kg of Aramite. At the end of the treatment, all the surviving animals show, on anatomo-pathological examination, malignant proliferation of the hepatic tissue and, in certain cases, of biliary ducts. This compound, proposed in the past as acaricide in agriculture, can thus be considered as a model substance for induction of malignant liver tumors.
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