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  • Title: Improvement of the antitumor activity of black currant polysaccharide by an enzymatic treatment.
    Author: Takata R, Yanai T, Yamamoto R, Konno T.
    Journal: Biosci Biotechnol Biochem; 2007 May; 71(5):1342-4. PubMed ID: 17485844.
    Abstract:
    A polysaccharide-rich substance isolated from black currant, named cassis polysaccharide (CAPS), was partially digested with beta-galactosidase from Aspergillus oryzae and its immunostimulatory activity was investigated. The in vitro cytokine-inducing effect of CAPS on RAW264 cells was gradually decreased along with lowering of the average MW of CAPS. In vivo, partially digested CAPS with a mean MW of approximately 20,000 showed the most potent antitumor activity against Ehrlich carcinoma in mice.
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