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  • Title: A case of cutaneous extravascular necrotizing granuloma without systemic manifestations.
    Author: Newell EL, Mallipeddi R, Murdoch ME, Groves R, Black MM, Robson A.
    Journal: Clin Exp Dermatol; 2007 Sep; 32(5):509-12. PubMed ID: 17489987.
    Abstract:
    Cutaneous extravascular necrotizing granuloma, an unusual palisading dermal granuloma, was first described by Churg and Strauss in 1951 in association with the syndrome of allergic granulomatosis (Churg-Strauss syndrome), for which it was though to be pathognomonic. It has subsequently been described in association with a number of autoimmune and immunoreactive diseases, and is regarded as a cutaneous marker of systemic pathology. To our knowledge, only one patient has been reported with clinical features confined to the skin. We report a 46-year-old woman with recurrent cutaneous lesions over a 10-year period and the classic histopathological pattern, but no underlying systemic disease.
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