These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The first direct enzymatic hydrolysis of alicyclic beta-amino esters: a route to enantiopure cis and trans beta-amino acids.
    Author: Forró E, Fülöp F.
    Journal: Chemistry; 2007; 13(22):6397-401. PubMed ID: 17492820.
    Abstract:
    The first direct enzymatic method is reported for the synthesis of cis and trans beta-amino acid enantiomers through the lipase-catalyzed enantioselective hydrolysis of alicyclic beta-amino esters in organic media. High enantioselectivities (E usually >100) were observed when the Candida antarctica lipase B catalyzed reactions were performed with H2O (0.5 equivalents) in iPr2O at 65 degrees C. The resolved products, obtained in good yields (>or=42%), could be easily separated.
    [Abstract] [Full Text] [Related] [New Search]