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  • Title: Anaphylactic reactions during immunotherapy.
    Author: Rezvani M, Bernstein DI.
    Journal: Immunol Allergy Clin North Am; 2007 May; 27(2):295-307, viii. PubMed ID: 17493504.
    Abstract:
    Subcutaneous immunotherapy (IT) with aeroallergen extracts is venerable treatment modality. The major risk associated with IT with commercial aeroallergen extracts is the uncommon occurrence of severe near-fatal or fatal anaphylaxis after injections. The objectives of this article are to review the reported incidences of severe anaphylaxis (near-fatal reactions and fatal reactions), define factors contributing to these events, and identify preventive measures that are likely to reduce or eliminate future fatal and near-fatal anaphylactic events. As with any treatment, anticipated benefits attributed to IT must be weighed against its potential risks.
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