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  • Title: Type A eagerness-energy across developmental periods predicts adulthood carotid intima-media thickness: the Cardiovascular Risk in Young Finns Study.
    Author: Keltikangas-Järvinen L, Hintsa T, Kivimäki M, Puttonen S, Juonala M, Viikari JS, Raitakari OT.
    Journal: Arterioscler Thromb Vasc Biol; 2007 Jul; 27(7):1638-44. PubMed ID: 17495237.
    Abstract:
    OBJECTIVE: We examined the Type A behavior across developmental periods as a predictor of adult carotid artery intima-media thickness (IMT). METHODS AND RESULTS: In this prospective cohort study of 408 men and 606 women, socioeconomic background and biological risk factors of participants were assessed at baseline at age 6 to 18 years of age, Type A behavior (Hunter-Wolf A-B Rating Scale) at the 6-, 9-, and 21-year follow-ups (subjects being 12 to 24, 15 to 27, and 27 to 39 years, respectively), and carotid IMT, adulthood socioeconomic situation, and biological risk factors at the 21-year follow-up when participants were at age 27 to 39 years of age. In men, the eagerness-energy component of Type A behavior, measured at any time point, was associated with thicker carotid IMT (P<0.008, P<0.04, P<0.03, and P<0.02 for the first, second, and third assessment, and for the average score, respectively), and this association was independent of early and adult risk factors. In women, the hard-driving component at baseline (P<0.04) but not later was independently related to thinner carotid IMT. The other components of Type A behavior (impatience-aggression and leadership) were not associated with IMT. CONCLUSIONS: Eagerness-energy component of Type A behavior over different developmental transitions seems to be a robust predictor of IMT in men.
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