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  • Title: Susceptibility of cyprinid cultured cells to cyprinid herpesvirus 3.
    Author: Davidovich M, Dishon A, Ilouze M, Kotler M.
    Journal: Arch Virol; 2007; 152(8):1541-6. PubMed ID: 17497237.
    Abstract:
    Cyprinid herpesvirus 3 is a highly contagious and lethal virus that affects ornamental koi and common carp worldwide. However, it is not yet known whether other cyprinids are infected and/or harbor the virus. Here, we report that cultured cells derived from common carp, koi, silver carp and goldfish allow CyHV-3 propagation, while cyprinid cells derived from fathead minnow and non-cyprinid cells derived from the channel catfish ovary are resistant to CyHV-3 infection. Interestingly, the epithelioma papulosum Cyprini cells derived from Cyprinus carpio are restrictive to the virus. These results indicate that CyHV-3 is not restricted to common carp and koi, but other cyprinids are also vulnerable to the virus.
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