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  • Title: Asymmetric synthesis of syn-alpha-substituted beta-amino ketones by using sulfinimines and prochiral Weinreb amide enolates.
    Author: Davis FA, Song M.
    Journal: Org Lett; 2007 Jun 07; 9(12):2413-6. PubMed ID: 17497798.
    Abstract:
    Syn-alpha-substituted beta-amino Weinreb amides are new chiral building blocks for asymmetric synthesis of syn-alpha-substituted beta-amino acids, aldehydes, and ketones and are prepared by addition of prochiral lithium enolates of Weinreb amides to sulfinimines (N-sulfinyl imines).
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