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  • Title: Percentage non-caeruloplasmin bound copper.
    Author: Twomey PJ, Wierzbicki AS, House IM, Viljoen A, Reynolds TM.
    Journal: Clin Biochem; 2007 Jun; 40(9-10):749-50. PubMed ID: 17498678.
    Abstract:
    OBJECTIVES: To compare percentage non-caeruloplasmin bound copper (%NCC) to generally accepted values. DESIGN AND METHODS: Using data for 338 normal individual patients, we calculated the %NCC. RESULTS: The %NCC ranged (median) from -59.75% to 51.98% (8.75%) respectively. The non-parametric reference interval was -23.44% to 22.99% with 43.8% of the %NCC values >10%. CONCLUSIONS: We found the %NCC to be higher than generally accepted. This may be due to uncertainty from precision, bias and specificity.
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