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  • Title: [Cyclosporine-induced gingival hyperplasia: report of one case].
    Author: Bahamondes C, Godoy J.
    Journal: Rev Med Chil; 2007 Mar; 135(3):370-4. PubMed ID: 17505584.
    Abstract:
    Gingival enlargement can be an adverse effect of cyclosporine A and nifedipine use. It has a high relapse rate if the drugs are not discontinued. There is a genetic predisposition to the development of this condition and dental biofilm can also play a role. We report a 64 years old male who received a renal allograft and was treated with cyclosporine and nifedipine. He required six surgical interventions for generalized gingival enlargement. After the sixth relapse, the patient was subjected to a periodontal treatment to eliminate the dental biofilm, which decreased the rate of recurrence of gingival enlargement.
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