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  • Title: The role of autoantibody-producing plasma cells in immune thrombocytopenic purpura refractory to rituximab.
    Author: Kuwana M, Iki S, Urabe A.
    Journal: Am J Hematol; 2007 Sep; 82(9):846-8. PubMed ID: 17506067.
    Abstract:
    Rituximab is becoming popular as a treatment for immune thrombocytopenic purpura (ITP). We report here a patient with ITP, who initially responded to rituximab, but later became refractory. In this patient, the appearance of plasma cells producing anti-platelet autoantibodies is likely to be one of the mechanisms for rituximab resistance.
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