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  • Title: Gingival hyperplasia in hyaline fibromatosis--a report of two cases.
    Author: Al-Malik MI, Bahatheq MA, Rehbini ZA.
    Journal: J Int Acad Periodontol; 2007 Apr; 9(2):42-8. PubMed ID: 17506383.
    Abstract:
    Hyaline fibromatosis is a rare inherited autosomal recessive disorder affecting connective tissue, characterized by an accumulation of hyaline material in the skin and other organs. This paper reports the oral findings of two cases of hyaline fibromatosis referred to our dental clinic due to extensive overgrowth of gingival tissue in the oral cavity that affected their eating and breathing. One patient was diagnosed with infantile systemic hyalinosis while the other was diagnosed with juvenile hyaline fibromatosis. Both cases showed similar clinical and histopathological findings, but one patient exhibited a more severe form of the disease, therefore it is difficult not to consider them as part of the same disorder. Children with such conditions have special dental needs, thus early dental consultation is important to begin caries prevention measures and dental therapy. No known therapy exists for hyaline fibromatosis. Currently, the only treatment is surgical excision of the lesions to improve esthetics and function.
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