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  • Title: Early embryo cleavage and day 2 mononucleation after intracytoplasmatic sperm injection for predicting embryo implantation potential in single embryo transfer cycles.
    Author: Sundström P, Saldeen P.
    Journal: Fertil Steril; 2008 Feb; 89(2):475-7. PubMed ID: 17509583.
    Abstract:
    In this study we analyzed the outcome of 275 fresh single embryo transfer cycles of day 2, mononucleate four-cell preembryos that had either cleaved early (n = 175) or not cleaved early (n = 100) 25 to 28 hours after intracytoplasmatic sperm injection. Neither the implantation rate nor the delivery rate showed any difference between the two groups, indicating that when a top-quality preembryo (mononucleate four-cell preembryo on day 2) is transferred, the presence of early cleavage seems to add no additional advantage in predicting the implantation potential of the preembryo.
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